According to a study, your body ages suddenly when you reach these two ages.

According to a study, your body ages suddenly when you reach these two ages.

If you’ve ever felt like the years are catching up with you and your body isn’t the same anymore, you may be right. New research out this week reveals that. An organism does not age linearly and gradually.But we pass Two periods of rapid change During adult life: between the ages of forty and sixty, which are the times when our number of molecules and microorganisms increases or decreases dramatically.

“We don’t change gradually over time; there are moments of radical change,” he says. Michael Snyderprofessor of genetics and director of genomics and personalized medicine at Stanford University and lead author of the study. According to Snyder, these are the moments of significant change that occur. Mid-40s (average 44) to early 60s, “This is true regardless of what type of particles we observe.”

Changes

In people aged 40 and over, researchers observed significant changes in the amount of molecules linked to blood metabolism.Alcoholthe Caffeine and FatsCardiovascular, skin and muscle diseases.

In people aged 60, the dramatic biomolecular changes they discovered were related to carbohydrate and caffeine metabolism, immune regulation, kidney function, cardiovascular disease, skin and muscle.

From the age of forty, you have to start taking care of yourself more.

From the age of forty, you have to start taking care of yourself more. Freebeck / Javier Sanchez Mengurans

In his presentation of the study, Snyder noted that some of these changes could be related toLifestyle Or behaviors that are concentrated in these age groups rather than being driven by biological factors. For example, impaired alcohol metabolism could be the result of higher alcohol consumption among those in their 40s because this is an often stressful life stage.

For this reason, the team that conducted the study published in Nature’s agingNow, he wants to investigate the factors driving these sets of changes. But regardless of the causes of these dramatic changes, the researchers say the fact that they are happening raises the need for people to pay attention to their health, especially When they are in their 40s and 60sFor example, they point out that when you reach the age of forty, you should reduce your alcohol consumption, as it has been observed that the ability to metabolize it slows down, and you should also increase your exercise to protect the heart and maintain muscle mass.

“I strongly believe that we should try to modify our lifestyle while we are still healthy,” Snyder said in announcing his findings.

Looking at it “in retrospect,” it fits into part of my clinical experience.

Jose Vina

Physiologist, Professor of Physiology and Gerontologist

The results of this study represent a major change in the concept of the aging process that doctors have adopted. “We had the impression that the organism finishes maturing at around the age of 30, and from that point on, we start aging in a fairly linear way. What this research reveals is that there are two critical stages in life – at the ages of 40 and 60 – when frailty increases and the body deteriorates more because the metabolites associated with aging change a lot at these two points.” Jose VinaProfessor of Physiology at the University of Valencia, who has been studying aging and longevity for more than 30 years.

The doctor says that Snyder’s team’s findings, analyzed “after the fact,” are consistent with much of his clinical experience. “There are diseases, like cardiovascular disease, that appear suddenly at age 40, and others, like neurodegenerative diseases, that appear at age 60. As a physician, I’ve seen this in many patients,” says Vinya.

He adds that after identifying these two critical stages, the key is to try to take good care of yourself at these ages to delay aging. He stresses that “care is an individual responsibility.”

Monitoring the biographies of more than a hundred people over the years has already led geneticist Michael Snyder and his colleagues at Stanford University to identify four com.ageotipus Or ways of aging. According to one Studying Published in Natural medicine In 2020, the kidneys, liver, metabolism, and immune systems age at different rates from each other and from person to person. Depending on the biological pathway in which the biomarkers of aging are most pronounced, a person can be classified into one of four types of aging—metabolic, immune, liver, and kidney—to try to predict which diseases are most likely to develop with age.
However, com.ageotipus They are not exclusive and a metabolic aging factor can also be an immunological aging factor, for example.

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